Scaffold attachment factor b1
WebMar 21, 2024 · SAFB (Scaffold Attachment Factor B) is a Protein Coding gene. Diseases associated with SAFB include Denys-Drash Syndrome and Breast Cancer . Among its … WebMay 20, 2011 · Scaffold attachment factor B1 (SAFB1) is a large multi-functional protein with functions in transcriptional repression, and RNA splicing. Recent suggestions indicate that it might also play a role in chromatin organization [7], [8]. SAFB1 is known to play a role in a variety of cellular processes [9], [10], [11].
Scaffold attachment factor b1
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WebOct 12, 2016 · Here we report a yeast two-hybrid screening identified FUS interaction with nuclear matrix-associated protein SAFB1 (scaffold attachment factor B1). FUS and SAFB1, abundant in chromatin-bound... WebAug 25, 2024 · The nuclear matrix protein Scaffold Attachment Factor B1 (SAFB1, SAFB) can act in prostate cancer (PCa) as an androgen receptor (AR) co-repressor that functions through epigenetic silencing of AR ...
WebFeb 21, 2024 · Scaffold attachment factor (SAFB) 1 and its homologue SAFB2 are multifunctional proteins that are involved in various cellular mechanisms, including chromatin organization and transcriptional regulation, and are also corepressors of estrogen receptor alpha (ERα). Both SAFBs are expressed at high levels in the brain. However, the … WebJun 15, 2024 · After DES treatment, colocalization of all ERR subtypes with scaffold attachment factor B1 (SAFB1), a nuclear matrix-associated protein, was observed in dot …
WebDec 11, 2009 · The examination of scaffold attachment factor B1 (SAFB1) and its multiple functions and tasks in cellular processes provides insight into its role in diseases, such as cancer. SAFB1 is a large multi-domain protein with well-described functions in transcriptional repression, and RNA splicing. WebMay 20, 2011 · Scaffold attachment factor B1 (SAFB1) is a large multi-functional protein with functions in transcriptional repression, and RNA splicing. Recent suggestions …
WebThe protein encoded by this gene, along with its paralog (scaffold attachment factor B1), is a repressor of estrogen receptor alpha. The encoded protein binds scaffold/matrix …
Webscaffold attachment factor B1 (SAFB1), a chromatin-associated protein linked to repression of nuclear receptors such as estrogen receptor-a,21–23 is a novel AR repressor, an MST1 … personalized kids step stoolWebJul 29, 2013 · Here we report that the nuclear matrix protein, scaffold attachment factor B1 (SAFB1), regulates AR activity and AR levels in a manner that suggests its involvement in … standard tv and appliance salem oregonWebThe examination of scaffold attachment factor B1 (SAFB1) and its multiple functions and tasks in cellular processes provides insight into its role in diseases, such as cancer. SAFB1 is a large multi‐domain protein with well‐described functions in transcriptional repression, and RNA splicing. personalized kids football jerseyWebAug 15, 2006 · Scaffold attachment factor B1 (SAFB1) is a multifunctional protein, which has previously been implicated in breast cancer. Here, we show that genetic deletion of SAFB1 in mouse embryonic fibroblasts (MEF) leads to spontaneous immortalization and altered expression of two proteins involved in immortalization and escape from … standard tv and appliance portland oregonWebSep 30, 2013 · Mukhopadhyay et al. have now identified the nuclear matrix protein scaffold attachment factor B1 (SAFB1) as a novel AR corepressor. The authors found that SAFB1 physically associates with AR... personalized kids stationery setsWebNational Center for Biotechnology Information standard tv and appliance saleWebJun 15, 2024 · After DES treatment, colocalization of all ERR subtypes with scaffold attachment factor B1 (SAFB1), a nuclear matrix-associated protein, was observed in dot-like subnuclear clusters, suggesting interactions of the ERRs with the nuclear matrix. personalized kids sherpa chair