Sprr2f-cre
Web23 Jul 2024 · BAC-Sprr2f-Cre is a BAC-transgenic line with Cre inserted into the Sprr2f locus, which is expressed exclusively in the endometrial epithelial cells that give rise to all … WebMETHOD: To further understand the role of Mig-6 and P4 in controlling uterine proliferation, we developed a Sprr2f-cre driven mouse model where Mig-6 is specifically ablated only in the epithelial cells of the uterus (Sprr2f RESULTS: Sprr2f CONCLUSIONS: These data suggest that endometrial epithelial cell proliferation is regulated by P4 mediated Mig-6 …
Sprr2f-cre
Did you know?
WebMethod: To further understand the role of Mig-6 and P4 in controlling uterine proliferation, we developed a Sprr2f-cre driven mouse model where Mig-6 is specifically ablated only in the epithelial cells of the uterus (Sprr2fcre+Mig-6f/f). We examined P4 effect and regulation of AKT signaling in the endometrium of mutant mice. WebThus, there might be room for further refinement of these Sprr2f-Cre mice. Nevertheless, Sprr2f-Cre; Lkb1 fl/fl mice develop invasive ECs and eventually die by 30 weeks of age …
Web24 Feb 2024 · Cre-ERT2 and Pten knockout mice were obtained from Jackson Laboratory. Sprr2f-Cre mice were provided by Dr. Leone. Cyclin D1 Flox/WT mice were generated in … WebEight-week-old C57BL/6J mice were used for embryo collection. Fsp1-Cre transgenic mice (012641) and ROSAmT/mG mice (007676) which have C57BL/6J congenic background were purchased from Jackson Laboratories (USA). ROSAmT/mG is a cell membrane-targeted, two-color fluorescent Cre-reporter allele. Without Cre recombination, membrane-localized
WebNotably, the Sprr2f-Cre model was completely penetrant and all female mice were dead approximately at 200 days. The uteri of the mice were shown to increase in mass with age, displaying malignant transformation throughout the tissue, whereas tumors in the Lkb1 +/− mice were focal. http://www.cancerindex.org/geneweb/ERRFI1.htm
Web26 Nov 2024 · In these prior studies, a 5.5-kb Sprr2f promoter fragment was fused to Cre to generate a “minigene” transgenic driver line Sprr2f-Cre, a.k.a. Tg(Sprr2f-cre) 1Dcas . This …
WebMutation details: A BAC derived 5.5 kb fragment of the Sprr2f promoter was cloned into a vector containing a cre coding sequence. Cre is expressed exclusively in endometrial … gummy bear necklace storeWeb12 Dec 2024 · Sprr2f-Cre;Pten fl/fl females have hyperplastic uterine remodeling and show malignant tumors confined within the endometrial compartment ( in-situ carcinoma). Approximately 50% of micedevelop endometrial tumors that invade into the myometrium (invasive carcinoma). gummy bear music cartoonWeb8 Mar 2010 · We identified a novel endometrial-specific gene, Sprr2f, and developed a Sprr2f-Cre transgene for conditional gene targeting within endometrial epithelium. We then used … gummy bear nesting dollsWeb26 Jan 2024 · Anti-mullerian hormone receptor type 2 ( Amhr2 )-Cre mice are mainly used to target genes in stromal and myometrial compartments of the uterus and oviduct as well as of the ovary. 10 Temporally, Cre action starts from midgestational embryo development (embryonic day 12.5) under the control of the Amhr2 promoter in Amhr2 -Cre mice. gummy bear music video with lyricsbowling green ky airport commercial flightsWebIdentification of Sprr2f as an estrogen-dependent gene that is specifically expressed in the uterus. (A) Digital northern representation, per Affymetrix 430 2.0 array data, of Sprr2f expression in... bowling green kentucky weather in marchWebNumber: Citing Articles: 1: Anuchina AA, Zaynitdinova MI, Demchenko AG, Evtushenko NA, Lavrov AV, Smirnikhina SA. Bridging Gaps in HDR Improvement: The Role of MAD2L2 ... bowling green kentucky weather forecast 7 day